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. 2017 May 16;46(5):773-775.
doi: 10.1016/j.immuni.2017.04.015.

CD4+ T Cell Activation and Vascular Normalization: Two Sides of the Same Coin?

Michele De Palma  1 , Rakesh K Jain  2
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CD4+ T Cell Activation and Vascular Normalization: Two Sides of the Same Coin?

Michele De Palma et al. Immunity. .
Free article

Abstract

Normalization of tumor blood vessels enhances the infiltration and functions of T cells. Tian et al. (2017) report that effector CD4+ T cells, in turn, support vascular normalization, highlighting intertwined roles for blood vessels and T cells in cancer.

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