Leveraging Human Genetics to Understand the Relation of LDL Cholesterol with Type 2 Diabetes
- PMID: 28515096
- PMCID: PMC5704957
- DOI: 10.1373/clinchem.2016.268565
Leveraging Human Genetics to Understand the Relation of LDL Cholesterol with Type 2 Diabetes
Conflict of interest statement
Dr. Ingelsson is a scientific advisor and consultant for Precision Wellness, Inc. and scientific advisor for Cellink for work unrelated to this paper. Dr. Knowles is Chief Medical Advisor for FH Foundation, a nonprofit organization dedicated to education, advocacy, and research of familial hypercholesterolemia.
Comment on
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Association Between Low-Density Lipoprotein Cholesterol-Lowering Genetic Variants and Risk of Type 2 Diabetes: A Meta-analysis.JAMA. 2016 Oct 4;316(13):1383-1391. doi: 10.1001/jama.2016.14568. JAMA. 2016. PMID: 27701660 Free PMC article.
References
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- Fall T, Xie W, Poon W, Yaghootkar H, Magi R, Consortium G et al. Using Genetic Variants to Assess the Relationship Between Circulating Lipids and Type 2 Diabetes. Diabetes. 2015;64(7):2676–84. - PubMed
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- Ference BA, Robinson JG, Brook RD, Catapano AL, Chapman MJ, Neff DR, et al. Variation in PCSK9 and HMGCR and Risk of Cardiovascular Disease and Diabetes. N Engl J Med. 2016;375(22):2144–53. - PubMed
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