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. 2017 May;15(5S):741-743.
doi: 10.6004/jnccn.2017.0089.

Multigene Testing for Hereditary Cancer: When, Why, and How

Kenneth Offit  1
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Multigene Testing for Hereditary Cancer: When, Why, and How

Kenneth Offit. J Natl Compr Canc Netw. 2017 May.

Abstract

Multigene testing is a complicated area, with advantages and disadvantages of testing for hereditary cancer syndromes. Currently, NCCN does not endorse routing multiplex testing outside of a research setting, and/or intensive genetic counseling regarding risks and benefits. The 2017 NCCN Clinical Practice Guidelines in Oncology for Genetic/Familial High-Risk Assessment: Breast and Ovarian and Colorectal provide suggestions for mutation carriers identified by panel tests.

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