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Review
. 2013 Apr 1;1(1):e24157.
doi: 10.4161/idp.24157. eCollection 2013 Jan-Dec.

What's in a name? Why these proteins are intrinsically disordered: Why these proteins are intrinsically disordered

A Keith Dunker  1 , M Madan Babu  2 , Elisar Barbar  3 , Martin Blackledge  4 , Sarah E Bondos  5 , Zsuzsanna Dosztányi  6 , H Jane Dyson  7 , Julie Forman-Kay  8 , Monika Fuxreiter  9 , Jörg Gsponer  10 , Kyou-Hoon Han  11 , David T Jones  12 , Sonia Longhi  13 , Steven J Metallo  14 , Ken Nishikawa  15 , Ruth Nussinov  16   17 , Zoran Obradovic  18 , Rohit V Pappu  19 , Burkhard Rost  20 , Philipp Selenko  21 , Vinod Subramaniam  22 , Joel L Sussman  23 , Peter Tompa  24   25   26 , Vladimir N Uversky  27   28
Affiliations
Review

What's in a name? Why these proteins are intrinsically disordered: Why these proteins are intrinsically disordered

A Keith Dunker et al. Intrinsically Disord Proteins. .

Abstract

"What's in a name? That which we call a rose By any other name would smell as sweet." From "Romeo and Juliet", William Shakespeare (1594) This article opens a series of publications on disambiguation of the basic terms used in the field of intrinsically disordered proteins. We start from the beginning, namely from the explanation of what the expression "intrinsically disordered protein" actually means and why this particular term has been chosen as the common denominator for this class of proteins characterized by broad structural, dynamic and functional characteristics.

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Figures

None
Figure 1. Protein intrinsic disorder Tower of Babel: some of the terms used in the literature to describe biologically active proteins without unique structures.
See this image and copyright information in PMC

References

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