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Review
. 2017 Mar;14 Suppl 1(Suppl 1):201-208.
doi: 10.17458/per.vol14.2017.yt.historygrowthhormone.

The History of Growth Hormone Treatment for GHD in Japan

Susumu Yokoya  1 , Toshiaki Tanaka  2
Affiliations
Review

The History of Growth Hormone Treatment for GHD in Japan

Susumu Yokoya et al. Pediatr Endocrinol Rev. 2017 Mar.

Abstract

In Japan, treatment of growth hormone deficiency with pituitary-extracted human growth hormone (phGH) was covered by health insurance for the first time in 1975. However, because of the shortage of phGH, the Foundation for Growth Science (FGS) was founded in 1977 to control the use of the product by its registration system and to collect pituitary glands in Japan. In 1986, recombinant human growth hormone was first approved. Since then, the FGS has been involved in the harmonization of growth hormone measurement, assessment for treatment eligibility according to the diagnostic criteria by the research group of the Ministry of Health and Welfare, and database generation and its utilization.

Keywords: Brain tumor; Correction formula; Diagnostic criteria; Growth hormone; Growth hormone deficiency; Leukemia; Specified chronic diseases in childhood.

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