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Comparative Study
. 1988 Nov;14(5):477-82.
doi: 10.1007/BF00521272.

Faithful and highly efficient RNA synthesis in isolated mitochondria from rat liver

P Cantatore  1 , P Loguercio Polosa, A Mustich, V Petruzzella, M N Gadaleta
Affiliations
Comparative Study

Faithful and highly efficient RNA synthesis in isolated mitochondria from rat liver

P Cantatore et al. Curr Genet. 1988 Nov.

Abstract

Isolated rat liver mitochondria in the presence of an appropriate incubation buffer are able to support DNA transcription and RNA processing in a way qualitatively and quantitatively similar to that used by intact cells. This system is also able to synthesize an RNA species of 155-175 nucleotides which probably corresponds to the 7S RNA, a type of RNA found so far only in growing cells. The role of this RNA in the mitochondrial replication and transcription processes, in relation to the cell metabolism, is discussed.

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