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. 2018 Feb;30(2):209-212.
doi: 10.1007/s40520-017-0771-2. Epub 2017 May 18.

Motivators for Alzheimer's disease clinical trial participation

Shoshana H Bardach  1   2 , Sarah D Holmes  3 , Gregory A Jicha  4   5
Affiliations

Motivators for Alzheimer's disease clinical trial participation

Shoshana H Bardach et al. Aging Clin Exp Res. 2018 Feb.

Abstract

Background: Alzheimer's disease (AD) research progress is impeded due to participant recruitment challenges. This study seeks to better understand, from the perspective of individuals engaged in clinical trials (CTs), research motivations.

Methods: Participants, or their caregivers, from AD treatment and prevention CTs were surveyed about research motivators.

Results: The 87 respondents had a mean age of 72.2, were predominantly Caucasian, 55.2% were male, and 56.3% had cognitive impairment. An overwhelming majority rated the potential to help themselves or a loved one and the potential to help others in the future as important motivators. Relatively few respondents were motivated by free healthcare, monetary rewards, or to make others happy.

Conclusions: Recruitment efforts should focus on the potential benefit for the individual, their loved ones, and others in the future rather than free healthcare or monetary rewards.

Keywords: Clinical trials; Motivation; Recruitment.

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Conflict of interest statement

Conflict of Interest: The authors declare that they have no conflict of interest.

Figures

Figure 1
Figure 1
Motivations for Participation – Self and Other Respondents
Figure 2
Figure 2
Gender Differences in Research Motivations
See this image and copyright information in PMC

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