Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2017 Sep;27(9):1081-1082.
doi: 10.1038/cr.2017.75. Epub 2017 May 19.

RIPped for neuroinflammation

Affiliations
Comment

RIPped for neuroinflammation

Bart Tummers et al. Cell Res. 2017 Sep.

Erratum in

  • RIPped for neuroinflammation.
    Tummers B, Green DR. Tummers B, et al. Cell Res. 2017 Aug;27(8):1074. doi: 10.1038/cr.2017.97. Cell Res. 2017. PMID: 28761169 Free PMC article. No abstract available.

Abstract

Activation of the receptor interacting serine/threonine kinase (RIPK) 3 mediates an inflammatory type of cell death called necroptosis; in addition, RIPK3 has necroptosis-independent roles in inflammation, although these are not well defined. In a recent study published in Cell, Daniels and colleagues demonstrate that RIPK3 controls West Nile virus infection by promoting neuroinflammation in the central nervous system without affecting neuronal death.

PubMed Disclaimer

Comment on

References

    1. Weinlich R, Oberst A, Beere HM, et al. Nat Rev Mol Cell Biol 2017; 18:127–136. - PubMed
    1. Moriwaki K, Chan FK. Cell Mol Life Sci 2016; 73:2325–2334. - PMC - PubMed
    1. Daniels BP, Snyder AG, Olsen TM, et al. Cell 2017; 169:301–313. - PMC - PubMed
    1. Shives KD, Tyler KL, Beckham JD. J Neuroimmunol 2017; 308:102–111. - PMC - PubMed
    1. Orozco S, Yatim N, Werner MR, et al. Cell Death Differ 2014; 21:1511–1521. - PMC - PubMed

Substances

LinkOut - more resources