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. 2016;37(5):436-438.

[Next generation sequencing]

[Article in French]
Affiliations
  • PMID: 28525213

[Next generation sequencing]

[Article in French]
M Le Mercier et al. Rev Med Brux. 2016.

Abstract

Fine needle aspiration is the gold standard method to differentiate benign thyroid nodules from malignant. However, for 15 to 30% of the cases the cytological diagnosis is indeterminate, leading to surgery. Integration of new molecular markers is opening new perspectives in order to increase the diagnostic precision of thyroid nodules with an indeterminate cytology.

La méthode diagnostique de référence pour différencier les nodules thyroïdiens bénins des nodules malins est la ponction écho-guidée à l’aiguille fine. Cependant dans 15 à 30 % des cas le diagnostic cytologique est indéterminé, menant à une intervention chirurgicale. L’intégration de nouveaux marqueurs moléculaires nous ouvrent de nouvelles perspectives pour augmenter la précision diagnostique des nodules thyroïdiens de diagnostic cytologique indéterminé.

Keywords: Fine needle aspiration; Molecular profile; Next generation sequencing; Thyroid nodules.

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