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. 2017 Aug;124(8):1247-1248.
doi: 10.1016/j.ophtha.2017.03.045. Epub 2017 May 16.

Metagenomic DNA Sequencing for the Diagnosis of Intraocular Infections

Thuy Doan  1 , Nisha R Acharya  1 , Benjamin A Pinsky  2 , Malaya K Sahoo  3 , Eric D Chow  4 , Niaz Banaei  2 , Indre Budvytiene  5 , Vicky Cevallos  6 , Lina Zhong  6 , Zhaoxia Zhou  6 , Thomas M Lietman  1 , Joseph L DeRisi  7
Affiliations

Metagenomic DNA Sequencing for the Diagnosis of Intraocular Infections

Thuy Doan et al. Ophthalmology. 2017 Aug.
No abstract available

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Figures

Figure 1
Figure 1. Detection of infectious agents by pathogen-directed PCRs and DNA-seq
(A) Metagenomic DNA sequencing identified 27 out of 31 (87%) infectious agents detected by pathogen-directed PCRs. (B) Metagenomic DNA sequencing detected bacteria, fungi, and DNA viruses in an additional 8 samples that were negative by pathogen-directed PCRs. Abbreviations: cytomegalovirus, CMV; herpes simplex virus, HSV; varicella zoster virus, VZV; Toxoplasma gondii, T. gondii; human T-cell leukemia virus type 1, HTLV-1; human herpesvirus 6, HHV-6.
See this image and copyright information in PMC

References

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