Comment on

• Dual angiopoietin-2 and VEGFA inhibition elicits antitumor immunity that is enhanced by PD-1 checkpoint blockade.

  Schmittnaegel M, Rigamonti N, Kadioglu E, Cassará A, Wyser Rmili C, Kiialainen A, Kienast Y, Mueller HJ, Ooi CH, Laoui D, De Palma M. Schmittnaegel M, et al. Sci Transl Med. 2017 Apr 12;9(385):eaak9670. doi: 10.1126/scitranslmed.aak9670. Sci Transl Med. 2017. PMID: 28404865
• Combined antiangiogenic and anti-PD-L1 therapy stimulates tumor immunity through HEV formation.

  Allen E, Jabouille A, Rivera LB, Lodewijckx I, Missiaen R, Steri V, Feyen K, Tawney J, Hanahan D, Michael IP, Bergers G. Allen E, et al. Sci Transl Med. 2017 Apr 12;9(385):eaak9679. doi: 10.1126/scitranslmed.aak9679. Sci Transl Med. 2017. PMID: 28404866 Free PMC article.