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Review
. 2017 Apr 28:6:597.
doi: 10.12688/f1000research.10876.1. eCollection 2017.

Recent advances in understanding HIV evolution

Sophie M Andrews  1 , Sarah Rowland-Jones  1
Affiliations
Review

Recent advances in understanding HIV evolution

Sophie M Andrews et al. F1000Res. .

Abstract

The human immunodeficiency virus (HIV) evolves rapidly owing to the combined activity of error-prone reverse transcriptase, recombination, and short generation times, leading to extensive viral diversity both within and between hosts. This diversity is a major contributing factor in the failure of the immune system to eradicate the virus and has important implications for the development of suitable drugs and vaccines to combat infection. This review will discuss the recent technological advances that have shed light on HIV evolution and will summarise emerging concepts in this field.

Keywords: HIV; evolution; mutation; recombinant.

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Conflict of interest statement

Competing interests: The authors confirm that they have no competing interests.No competing interests were disclosed.No competing interests were disclosed.

References

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    2. F1000 Recommendation

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