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Review
. 2017 Aug;22(4):377-381.
doi: 10.1097/MOT.0000000000000435.

Live donor kidney - PAK versus SPK: how to decide?

Erik Stites  1 , Alexander C Wiseman
Affiliations
Review

Live donor kidney - PAK versus SPK: how to decide?

Erik Stites et al. Curr Opin Organ Transplant. 2017 Aug.

Abstract

Purpose of review: Patients with type 1 diabetes and end stage renal disease face a complex choice when considering the relative risks and benefits of kidney transplant alone with or without subsequent pancreas after kidney transplant (PAK) or simultaneous kidney pancreas transplant (SPK).

Recent findings: SPK is considered the optimal treatment regarding long-term patient survival, but when also faced with the option of living donor kidney transplant with the potential for PAK later, the ideal option is less clear.

Summary: This review summarizes the current literature regarding SPK, living donor kidney transplant alone, and PAK transplant outcomes and examines the relative risks of pre- and posttransplant variables that impact patient and graft survival to help inform this complex treatment decision.

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