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Multicenter Study
. 2017 Mar-Apr;92(2):277-278.
doi: 10.1590/abd1806-4841.20175121.

Study of 448 cases of melanoma in situ in two hospitals in Rio de Janeiro

Luciana Pantaleão  1 , Mayra Carrijo Rochael  1
Affiliations
Multicenter Study

Study of 448 cases of melanoma in situ in two hospitals in Rio de Janeiro

Luciana Pantaleão et al. An Bras Dermatol. 2017 Mar-Apr.

Abstract

The diagnosis of cutaneous melanoma in situ, considered to have excellent prognosis, has been increasingly frequent, with rare isolated reports of cutaneous melanoma in situ presenting recurrence, metastasis, and death. No specific study is found in the literature about these lesions of unexpected behavior. We describe the demographic and histopathological findings of 448 cases of cutaneous melanoma in situ in 369 patients, emphasizing the prognostic criteria of those with unfavorable outcomes, corresponding to 9 cases in which regression had no significant role. Adnexotropism was found in 44.5% of cases. The study of early lesions would allow clinicians to have a better understanding of the evolutionary processes of the disease.

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Conflict of interest statement

Conflict of interest: none.

Figures

Figure 1
Figure 1
Case No. 112 – Melanoma in situ with extensive tropism for adnexal structures that developed regional metastasis. Case No. 294 – Melanoma in situ with expansive junctional nests; the case presented local recurrence.
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