Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 Apr-Jun;12(2):205-211.
doi: 10.4103/jovr.jovr_66_17.

Infantile Periocular Hemangioma

Mehdi Tavakoli  1   2 , Saeid Yadegari  1 , Mahnaz Mosallaei  1 , Maryam Aletaha  1 , Hossein Salour  1 , Wendy W Lee  2
Affiliations
Review

Infantile Periocular Hemangioma

Mehdi Tavakoli et al. J Ophthalmic Vis Res. 2017 Apr-Jun.

Abstract

Infantile periocular hemangiomas (IPH) are common benign vascular tumors that present early in childhood. They typically show a rapid nonlinear growth pattern a few weeks after birth during a proliferative phase, then continue with an involution phase and may result in serious ocular or systemic complications. Theses tumors may present in a range of small isolated lesions to multiple, diffuse involvements. Understanding the nature of the disease, the natural course, complications, indications for intervention, and treatment modalities would be helpful for ophthalmologists, who will likely be consulted for periocular cases. In this review, we present recent opinions about the pathogenesis, diagnosis, and treatment options for patients with IPH.

Keywords: Amblyopia; Children Eyelid Lesion; Corticosteroid Injection; Infantile Periocular Hemangioma; Systemic Propranolol.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Various presentations of periocular infantile hemangioma. Upper left: superficial, upper lid; upper right: deep upper lid and ocular surface; middle left: superficial lower lid; middle right: deep lower lid; lower left: extensive facial involvement; lower right: orbital involvement (confirmed by incisional biopsy).
Figure 2
Figure 2
Periocular infantile hemangioma at presentation (left, upper) and at 1 month (right upper), 3 months (left lower), and 12 months (right lower) after treatment with systemic propranolol and intralesional corticosteroid injection.
Figure 3
Figure 3
Infantile hemangioma with extensive hemifacial involvement before (left) and 2 months after (right) systemic propranolol.
See this image and copyright information in PMC

References

    1. Dasgupta R, Fishman SJ. ISSVA classification. Semin Pediatr Surg. 2014;23:158–161. - PubMed
    1. Maguiness SM, Frieden IJ. Current management of infantile hemangiomas. Semin Cutan Med Surg. 2010;29:106–114. - PubMed
    1. Chang LC, Haggstrom AN, Drolet BA, Baselga E, Chamlin SL, Garzon MC, et al. Growth characteristics of infantile hemangiomas: Implications for management. Pediatrics. 2008;122:360–367. - PubMed
    1. Tollefson MM, Frieden IJ. Early growth of infantile hemangiomas: What parents' photographs tell us? Pediatrics. 2012;130:e314–320. - PubMed
    1. Kilcline C, Frieden IJ. Infantile hemangiomas: How common are they? A systematic review of the medical literature. Pediatr Dermatol. 2008;25:168–173. - PubMed