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. 2017 Apr 5;2(3):136-142.
doi: 10.7150/jbji.18408. eCollection 2017.

Brucella melitensis prosthetic joint infection

Domenica Flury  1 , Henrik Behrend  2 , Parham Sendi  3 , Matthias von Kietzell  1 , Carol Strahm  1
Affiliations

Brucella melitensis prosthetic joint infection

Domenica Flury et al. J Bone Jt Infect. .

Abstract

Periprosthetic joint infection (PJI) due to Brucella spp. is rare. We report a case in a 75-year-old man and review 29 additional cases identified in a literature search. The diagnosis of Brucella PJI is challenging, in particular in non-endemic countries. Serological tests prior to joint aspiration or surgical intervention are reasonable. Involvement of infection control and timely information to laboratory personnel is mandatory upon diagnosis. There is no uniform treatment concept, neither with respect to surgical intervention nor for the duration of antimicrobials. Most cases have a successful outcome, irrespective of surgical modality, and with an antimicrobial combination regimen for 12 or more weeks.

Keywords: Brucella; Periprosthetic joint infection.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interest exists.

Figures

Figure 1
Figure 1
Initial anteroposterior (a) and lateral (b) radiographs at referral showing a loose and displaced femoral and tibial component. Anteroposterior (c) and lateral (d) radiographs at follow-up 2 years after reimplantation.
Figure 2
Figure 2
Flow-chart for literature research.
See this image and copyright information in PMC

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References

    1. Agarwal S, Kadhi SK, Rooney RJ. Brucellosis complicating bilateral total knee arthroplasty. Clin Orthop Relat Res; 1991. pp. 179–81. - PubMed
    1. Atay T, Baydar ML, Heybeli N. [Brucellar Prosthetic Infection After Total Knee Arthroplasty: A Case With Retained Prosthesis by Arthroscopic and Medical Treatment] Trakya Univ Tip Fak Derg. 2008;25:252–255.
    1. Cairo M, Calbo E, Gomez L, Matamala A, Asuncion J, Cuchi E. et al. Foreign-body osteoarticular infection by Brucella melitensis: A report of three cases. J Bone Joint Surg Am. 2006;88:202–4. - PubMed
    1. Carothers JT, Nichols MC, Thompson DL. Failure of total hip arthroplasty secondary to infection caused by Brucella abortus and the risk of transmission to operative staff. Am J Orthop (Belle Mead NJ) 2015;44:E42–5. - PubMed
    1. Dauty M, Dubois C, Coisy M. Bilateral knee arthroplasty infection due to Brucella melitensis: a rare pathology? Joint Bone Spine. 2009;76:215–6. - PubMed