Comparative Study
[Effect of ascorbic acid on the hepatocarcinogenic action of N-nitrosodiethylamine in rats]
[Article in
Russian]
- PMID: 2854047
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Comparative Study
[Effect of ascorbic acid on the hepatocarcinogenic action of N-nitrosodiethylamine in rats]
[Article in
Russian]
Eksp Onkol.
1988.
Abstract
It is shown that the ascorbic acid (AA) administration to Wistar male rats (50 mg per animal intraperitoneally 3 times a week) accelerates hepatocarcinogenesis induced by N-nitrosodiethylamine (2.5 mg/kg 6 times a week in drinking water). In this case the activity of glucose-6-phosphate dehydrogenase in liver increases, while that of glucose-6-phosphatase decreases.
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