Consensus Recommendations for the Clinical Application of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Depression
- PMID: 28541649
- PMCID: PMC5846193
- DOI: 10.4088/JCP.16cs10905
Consensus Recommendations for the Clinical Application of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Depression
Abstract
Objective: To provide expert recommendations for the safe and effective application of repetitive transcranial magnetic stimulation (rTMS) in the treatment of major depressive disorder (MDD).
Participants: Participants included a group of 17 expert clinicians and researchers with expertise in the clinical application of rTMS, representing both the National Network of Depression Centers (NNDC) rTMS Task Group and the American Psychiatric Association Council on Research (APA CoR) Task Force on Novel Biomarkers and Treatments.
Evidence: The consensus statement is based on a review of extensive literature from 2 databases (OvidSP MEDLINE and PsycINFO) searched from 1990 through 2016. The search terms included variants of major depressive disorder and transcranial magnetic stimulation. The results were limited to articles written in English that focused on adult populations. Of the approximately 1,500 retrieved studies, a total of 118 publications were included in the consensus statement and were supplemented with expert opinion to achieve consensus recommendations on key issues surrounding the administration of rTMS for MDD in clinical practice settings.
Consensus process: In cases in which the research evidence was equivocal or unclear, a consensus decision on how rTMS should be administered was reached by the authors of this article and is denoted in the article as "expert opinion."
Conclusions: Multiple randomized controlled trials and published literature have supported the safety and efficacy of rTMS antidepressant therapy. These consensus recommendations, developed by the NNDC rTMS Task Group and APA CoR Task Force on Novel Biomarkers and Treatments, provide comprehensive information for the safe and effective clinical application of rTMS in the treatment of MDD.
© Copyright 2017 Physicians Postgraduate Press, Inc.
Comment in
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Consensus Recommendations for rTMS in Depression: Not Entirely Correct!J Clin Psychiatry. 2018 Jan/Feb;79(1):17lr11851. doi: 10.4088/JCP.17lr11851. J Clin Psychiatry. 2018. PMID: 29505181 No abstract available.
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Dr McClintock and Colleagues Reply.J Clin Psychiatry. 2018 Jan/Feb;79(1):17lr11851a. doi: 10.4088/JCP.17lr11851a. J Clin Psychiatry. 2018. PMID: 29505182 No abstract available.
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Roles and Qualifications of TMS Treatment Team Members.J Clin Psychiatry. 2018 Jan/Feb;79(1):17lr11887. doi: 10.4088/JCP.17lr11887. J Clin Psychiatry. 2018. PMID: 29505183 No abstract available.
References
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- Greden JF. The burden of recurrent depression: causes, consequences, and future prospects. J Clin Psychiatry. 2001;62(suppl 22):5–9. - PubMed
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- Janicak PG, O’Reardon JP, Sampson SM, et al. Transcranial magnetic stimulation in the treatment of major depressive disorder: a comprehensive summary of safety experience from acute exposure, extended exposure, and during reintroduction treatment. J Clin Psychiatry. 2008;69(2):222–232. doi: 10.408/JCP.v69n0208. - DOI - PubMed
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