Angiomyofibroblastoma of the Foot: a Rare Soft Tissue Tumor at Unusual Site

Abstract

Angiomyofibroblastoma is a rare benign soft tissue tumor that arises predominantly in the female genital tract. It occurs less commonly in the scrotum, spermatic cord, and the retroperitoneum. Its diagnosis is based on specific histological and immunopathological features. However, the condition has never been previously described in the extremities. We present the first case report of angiomyofibroblastoma presenting as a slow-growing tumor in the foot of a 48-year-old lady.

Keywords: Angiomyofibroblastoma; Foot; Soft tissue tumor.

Fig. 1

Clinical photographs showing a firm lobulated soft tissue mass measuring 7 × 6 cm in the medial aspect of the left foot

Fig. 2

T2W MRI scans of the left foot demonstrating a T2 hyperintense tumor mass in the midfoot, displacing the flexor digitorum tendons inferiorly, closely related to branches of the medial plantar nerve, and involving the plantar skin

Fig. 3

Macroscopic features of the tumor in cross-section

Fig. 4

Microscopic features of the tumor

Fig. 5

Immuno-histochemical staining showed strongly ER staining positive