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. 2017 May 18;10(5):728-732.
doi: 10.18240/ijo.2017.05.11. eCollection 2017.

Modified deep sclerectomy combined with Ex-PRESS filtration device versus trabeculectomy for primary open angle glaucoma

Vassilios Kozobolis  1   2   3 , Georgios D Panos  2 , Aristeidis Konstantinidis  1 , Miguel Teus  4 , Georgios Labiris  1   2
Affiliations

Modified deep sclerectomy combined with Ex-PRESS filtration device versus trabeculectomy for primary open angle glaucoma

Vassilios Kozobolis et al. Int J Ophthalmol. .

Abstract

Aim: To compare the efficacy of modified deep sclerectomy combined with Ex-PRESS shunt versus trabeculectomy in primary open angle glaucoma.

Methods: This is a prospective cohort comparative single-center study. Forty-nine eyes of 49 patients were enrolled in the study. Patients were randomly divided into two groups. Group A (22 patients) underwent classic trabeculectomy and group B (27 patients) underwent modified deep sclerectomy combined with insertion of Ex-PRESS model P50 drainage device.

Results: Mean age was 69±7y in group A and 64±8y in group B (P=0.03). The mean reduction was 11.1±5.7 mm Hg in group A compared to 15.8±5.7 mm Hg in group B at 6mo (P=0.006), and 9.8±4.9 mm Hg and 15.4±4.7 mm Hg respectively at 1y (P=0.0001). Regarding the postoperative glaucoma medication, significant difference was observed between the two groups (in favour of group B) only at 6mo (P=0.017). At the end of the follow-up period complete success rate in group A was 68.2% compared to 92.6% in group B (χ2 test, P=0.07) and qualified success rate was 100% in both groups.

Conclusion: Modified deep sclerectomy combined with Ex-PRESS shunt may provide comparable IOP reduction with fewer complications in management of primary open angle glaucoma.

Keywords: Ex-PRESS drainage device; glaucoma; modified deep sclerectomy; trabeculectomy.

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Figures

Figure 1
Figure 1. Mean IOP overtime in eyes undergoing MDS-Xpress or trabeculectomy.
Figure 2
Figure 2. Preoperative and 12mo postoperative IOP in both groups.
Figure 3
Figure 3. Kaplan-Meier medicine free survival curves in both groups.
See this image and copyright information in PMC

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