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Case Reports
. 2017 Aug;42(4):506-508.
doi: 10.1111/jcpt.12538. Epub 2017 May 25.

Survival without peripheral neuropathy after massive acute arsenic poisoning: Treated by 2,3-dimercaptopropane-1-sulphonate

P-H Lu  1 , J-C Tseng  2 , C-K Chen  2 , C-H Chen  1
Affiliations
Case Reports

Survival without peripheral neuropathy after massive acute arsenic poisoning: Treated by 2,3-dimercaptopropane-1-sulphonate

P-H Lu et al. J Clin Pharm Ther. 2017 Aug.

Abstract

What is known and objective: Massive acute arsenic poisoning is rare yet potentially life-threatening. 2,3-dimercaptopropane-1-sulphonate (DMPS) appears to have the appropriate chelating property. However, clinical experience on the use of DMPS in massive arsenic poisoning is limited.

Case description: A 37-year-old woman attempted suicide by ingesting 37.5 g of arsenic trioxide. DMPS was promptly initiated based on history and clinical symptoms. The patient recovered completely, with no complications or side effects of the therapy.

What is new and conclusion: TDMPS is useful for the treatment of massive acute arsenic poisoning.

Keywords: 2,3-dimercaptopropane-1-sulphonate; arsenic; arsenic poisoning; chelation therapy.

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