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Observational Study
. 2017 Jul-Aug;21(4):468-471.
doi: 10.1016/j.bjid.2017.04.003. Epub 2017 May 23.

A prospective observational cohort study to assess the incidence of acute otitis media among children 0-5 years of age in Southern Brazil

Tatiana M Lanzieri  1 , Clóvis Arns da Cunha  2 , Rejane B Cunha  3 , D Fermin Arguello  4 , Raghavendra Devadiga  5 , Nervo Sanchez  6 , Eduardo Ortega Barria  4
Affiliations
Observational Study

A prospective observational cohort study to assess the incidence of acute otitis media among children 0-5 years of age in Southern Brazil

Tatiana M Lanzieri et al. Braz J Infect Dis. 2017 Jul-Aug.

Abstract

Objectives: To estimate acute otitis media incidence among young children and impact on quality of life of parents/caregivers in a southern Brazilian city.

Methods: Prospective cohort study including children 0-5 years of age registered at a private pediatric practice. Acute otitis media episodes diagnosed by a pediatrician and impact on quality of life of parents/caregivers were assessed during a 12-month follow-up.

Results: During September 2008-March 2010, of 1,136 children enrolled in the study, 1074 (95%) were followed: 55.0% were ≤2 years of age, 52.3% males, 94.7% white, and 69.2% had previously received pneumococcal vaccine in private clinics. Acute otitis media incidence per 1000 person-years was 95.7 (95% confidence interval: 77.2-117.4) overall, 105.5 (95% confidence interval: 78.3-139.0) in children ≤2 years of age and 63.6 (95% confidence interval: 43.2-90.3) in children 3-5 years of age. Acute otitis media incidence per 1000 person-years was 86.3 (95% confidence interval: 65.5-111.5) and 117.1 (95% confidence interval: 80.1-165.3) among vaccinated and unvaccinated children, respectively. Nearly 68.9% of parents reported worsening of their overall quality of life.

Conclusion: Acute otitis media incidence among unvaccinated children in our study may be useful as baseline data to assess impact of pneumococcal vaccine introduction in the Brazilian National Immunization Program in April 2010.

Keywords: Acute otitis media; Children; Incidence; Quality of life.

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Figures

Fig. 1
Fig. 1
Distribution of QoL impact score. It presents the responses (with percentage of responders) to the quality of life questionnaire, by overall score and individual emotional or daily disturbance subscores. QoL, quality of life.
See this image and copyright information in PMC

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