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Review
. 2017:132:361-379.
doi: 10.1016/bs.irn.2017.03.002. Epub 2017 May 3.

Treatment of Nonmotor Symptoms in Parkinson's Disease

Anna Sauerbier  1 , Ilaria Cova  2 , Miguel Rosa-Grilo  3 , Raquel N Taddei  3 , Laurie K Mischley  4 , K Ray Chaudhuri  5
Affiliations
Free article
Review

Treatment of Nonmotor Symptoms in Parkinson's Disease

Anna Sauerbier et al. Int Rev Neurobiol. 2017.
Free article

Abstract

Nonmotor symptoms (NMS) are integral to Parkinson's disease (PD) and the management can often be challenging. In spite of the growing evidence that NMS have a key impact on the quality of life of patients and caregivers, most clinical trials still focus on motor symptoms as primary outcomes. As a consequence strong evidence-based treatment recommendations for NMS occurring in PD are spare. In this chapter, the current data addressing the treatment of major NMS such as sleep, cognitive and autonomic dysfunction, and depression and anxiety are described.

Keywords: Nonmotor symptoms; Parkinson's disease; Treatment.

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