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. 2017 Jul/Aug;63(4):456-463.
doi: 10.1097/MAT.0000000000000603.

Pediatric Extracorporeal Life Support Organization Registry International Report 2016

Affiliations

Pediatric Extracorporeal Life Support Organization Registry International Report 2016

Ryan P Barbaro et al. ASAIO J. 2017 Jul/Aug.

Abstract

The purpose of this report is to describe the international growth, outcomes, complications, and technology used in pediatric extracorporeal life support (ECLS) from 2009 to 2015 as reported by participating centers in the Extracorporeal Life Support Organization (ELSO). To date, there are 59,969 children who have received ECLS in the ELSO Registry; among those, 21,907 received ECLS since 2009 with an overall survival to hospital discharge rate of 61%. In 2009, 2,409 ECLS cases were performed at 157 centers. By 2015, that number grew to 2,992 cases in 227 centers, reflecting a 24% increase in patients and 55% growth in centers. ECLS delivered to neonates (0-28 days) for respiratory support was the largest subcategory of ECLS among children <18-years old. Overall, 48% of ECLS was delivered for respiratory support and 52% was for cardiac support or extracorporeal life support to support cardiopulmonary resuscitation (ECPR). During the study period, over half of children were supported on ECLS with centrifugal pumps (51%) and polymethylpentene oxygenators (52%). Adverse events including neurologic events were common during ECLS, a fact that underscores the opportunity and need to promote quality improvement work.

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Conflict of interest statement

Conflict of Interest: Drs. Barbaro and Thiagarajan are on the steering committee for the Extracorporeal Life Support Organization. Dr. Barbaro is the ELSO Registry Chair and Dr. Thiagarajan is the immediate past Registry Chair. The authors have no other conflicts of interest relevant to this article to disclose.

Figures

Figure 1
Figure 1
Number of Reporting ELSO Center and Patient Counts, 2009–2015
Figure 2
Figure 2
ECLS Survival by Age Group and Support Type, 2009–2015
Figure 3
Figure 3
Trends in ECLS Support Type, 2009–2015
Figure 4
Figure 4
Trends in ECLS Mechanical Pump Type, 2009–2015
Figure 5
Figure 5
Trends in ECLS Membrane Oxygenator, 2009–2015
Figure 6
Figure 6
Trends in use of venovenous cannulation for respiratory support ECLS, 2009–2015

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