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. 2017 Jun;139(6):e20164114.
doi: 10.1542/peds.2016-4114.

Reducing Hospitalization Rates for Children With Anaphylaxis

Affiliations

Reducing Hospitalization Rates for Children With Anaphylaxis

Karen S Farbman et al. Pediatrics. 2017 Jun.

Abstract

Background and objectives: Most children with anaphylaxis in the emergency department (ED) are hospitalized. Opportunities exist to safely reduce the hospitalization rate for children with anaphylaxis by decreasing unnecessary hospitalizations. A quality improvement (QI) intervention was conducted to improve care and reduce hospitalization rates for children with anaphylaxis.

Methods: We used the Model for Improvement and began with development and implementation in 2011 of a locally developed evidence-based guideline based on national recommendations for the management of anaphylaxis. Guideline adoption and adherence were supported by interval reminders and feedback to providers. Patients from 2008 to 2014 diagnosed with anaphylaxis were identified, and statistical process control methods were used to evaluate change in hospitalization rates over time. The balancing measure was any return visit to the ED within 72 hours. To control for secular trends, hospitalization rates for anaphylaxis at 34 US children's hospitals over the same time period were analyzed.

Results: Over the study period, there were 1169 visits for children with anaphylaxis, of which 731 (62%) occurred after the QI implementation. The proportion of children hospitalized decreased from 54% to 36%, with no increase in the 72-hour ED revisit rate. The hospitalization rate across 34 other US pediatric hospitals remained static at 52% over the study period.

Conclusions: We safely reduced unnecessary hospitalizations for children with anaphylaxis and sustained the change over 3 years by using a QI initiative that included evidence-based guideline development and implementation, reinforced by provider reminders and structured feedback.

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Conflict of interest statement

POTENTIAL CONFLICT OF INTEREST: The authors have indicated they have no potential conflicts of interest to disclose.

Figures

FIGURE 1
FIGURE 1
Key driver diagram for reduction of hospitalizations of patients with anaphylaxis.
FIGURE 2
FIGURE 2
Statistical process control chart showing hospitalization rate over time with control limits set at 3-σ and annotations (time of EBG introduction and interventions). LCL, lower control limit; UCL, upper control limit.
FIGURE 3
FIGURE 3
Cumulative summary chart of anaphylaxis admissions avoided since introduction of EBG.
FIGURE 4
FIGURE 4
Mean hospitalization rate according to quarter for the 34 children’s hospitals by using the Pediatric Health Information System database.

References

    1. Michelson KA, Monuteaux MC, Neuman MI. Variation and trends in anaphylaxis care in United States children’s hospitals. Acad Emerg Med. 2016;23(5):623–627 - PubMed
    1. Jackson KD, Howie LD, Akinbami LJ. Trends in allergic conditions among children: United States, 1997-2011. NCHS Data Brief. 2013;(121):1–8 - PubMed
    1. Campbell RL, Li JT, Nicklas RA, Sadosty AT; Members of the Joint Task Force; Practice Parameter Workgroup . Emergency department diagnosis and treatment of anaphylaxis: a practice parameter. Ann Allergy Asthma Immunol. 2014;113(6):599–608 - PubMed
    1. Rohacek M, Edenhofer H, Bircher A, Bingisser R. Biphasic anaphylactic reactions: occurrence and mortality. Allergy. 2014;69(6):791–797 - PubMed
    1. Bekmezian A, Fee C, Weber E. Clinical pathway improves pediatrics asthma management in the emergency department and reduces admissions. J Asthma. 2015;52(8):806–814 - PMC - PubMed