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. 2017 Jan-Mar;8(1):116-121.
doi: 10.4103/ccd.ccd_836_16.

Effect of Freeze Dried Powdered Probiotics on Gingival Status and Plaque Inhibition: A Randomized, Double-blind, Parallel Study

Asif Yousuf  1 , Mohsin Sidiq  2 , Shravani Ganta  3 , Anup Nagaraj  3 , Preeti Vishnani  4 , Iram Jan  5
Affiliations

Effect of Freeze Dried Powdered Probiotics on Gingival Status and Plaque Inhibition: A Randomized, Double-blind, Parallel Study

Asif Yousuf et al. Contemp Clin Dent. 2017 Jan-Mar.

Abstract

Objective: The study aimed to evaluate the effectiveness of freeze dried powdered probiotics on gingival status and plaque inhibition among 12-15-year-old schoolchildren.

Materials and methods: This randomized controlled trial was conducted among 12-15-year-old schoolchildren in Jaipur. Commercially available freeze dried probiotics containing Lactobacillus acidophilus, Bifidobacterium longum, Bifidobacterium bifidum and Bifidobacterium lactis (Prowel, Alkem Laboratories), lactic acid bacillus only (Sporolac, Sangyo), and a placebo powder calcium carbonate 250 g (Calcium Sandoz, Novartis) were assigned to two intervention groups and a placebo group each comprising 11 schoolchildren. All subjects were instructed to mix the powder in 30 ml of water and swish once daily for 3 min, for 3 weeks. Periodontal clinical parameters were assessed by examining the subjects for Turesky-Gilmore-Glickman plaque index (PI) (Modification of Quigley-Hein PI) and gingival index at baseline, 7th day, 14th day, and 21st day.

Results: For both the probiotic groups, a statistically significant reduction (P < 0.05) in gingival status and plaque inhibition was recorded up to 2nd week of probiotic ingestion. However, no significant difference was observed in the placebo group.

Conclusion: The use of probiotic mouth rinses improves the oral health in children by significantly reducing the plaque and gingival scores. Further studies are warranted to prove or refute the long-term effects, means of administering probiotics and the dosages needed to achieve different preventive or therapeutic purposes.

Keywords: Bacteriotherapy; Bifidobacteria; Lactobacillus; oral ecology; probiotic.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Examinations for the plaque index (Turesky modification of Quigley Hein plaque index)
Figure 2
Figure 2
Overview of the methodology
Figure 3
Figure 3
Gingival and plaque scores during subsequent weekly intervals in Group A
Figure 4
Figure 4
Gingival and plaque scores during subsequent weekly intervals in Group B
Figure 5
Figure 5
Gingival and plaque scores during subsequent weekly intervals in Group C
See this image and copyright information in PMC

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