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. 2017 Jul;12(7):1289-1294.
doi: 10.1038/nprot.2017.040. Epub 2017 Jun 1.

Quantitative proteomics: challenges and opportunities in basic and applied research

Olga T Schubert  1 , Hannes L Röst  2 , Ben C Collins  3 , George Rosenberger  3 , Ruedi Aebersold  3   4
Affiliations
Free article

Quantitative proteomics: challenges and opportunities in basic and applied research

Olga T Schubert et al. Nat Protoc. 2017 Jul.
Free article

Abstract

In this Perspective, we discuss developments in mass-spectrometry-based proteomic technology over the past decade from the viewpoint of our laboratory. We also reflect on existing challenges and limitations, and explore the current and future roles of quantitative proteomics in molecular systems biology, clinical research and personalized medicine.

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