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. 2017 Jun 1;11(6):e0005438.
doi: 10.1371/journal.pntd.0005438. eCollection 2017 Jun.

Introducing the TrypanoGEN biobank: A valuable resource for the elimination of human African trypanosomiasis

Affiliations

Introducing the TrypanoGEN biobank: A valuable resource for the elimination of human African trypanosomiasis

Hamidou Ilboudo et al. PLoS Negl Trop Dis. .
No abstract available

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Age frequencies of case and control participants.
Many participants did not know their age, and approximate ages were assigned to many subjects, leading to large spikes of numbers at 30, 40, 50, and 60 years, with minor spikes at 5-year intervals. These spikes were smoothed using a moving-window average over 10 years. The mean ages of Trypanosoma brucei gambiense and T. b. rhodesiense case and control participants were 36 and 42, respectively. The age distributions were similar except that the T. b. rhodesiense subjects’ ages were shifted to the right.
Fig 2
Fig 2. Map showing countries from which samples were collected and the proportion of each type of subject in the collection.
Stars indicate locations of biobank hubs.

References

    1. WHO. Control and surveillance of human African trypanosomiasis. WHO Technical Report Series. 2013; 984 Geneva. - PubMed
    1. WHO. Lowest caseload recorded as the world prepares to defeat sleeping sickness. 2016; http://www.who.int/neglected_diseases/news/HAT_lowest_caseload_recorded/en/.
    1. Bucheton B, MacLeod A, Jamonneau V. Human host determinants influencing the outcome of Trypanosoma brucei gambiense infections. Parasite Immunol. 2011; 33: 438–447. 10.1111/j.1365-3024.2011.01287.x - DOI - PMC - PubMed
    1. Checchi F, Filipe JA, Barrett MP, Chandramohan D. The natural progression of Gambiense sleeping sickness: what is the evidence? PLoS Negl Trop Dis. 2008; 2: e303 10.1371/journal.pntd.0000303 - DOI - PMC - PubMed
    1. Sternberg JM, Maclean L. A spectrum of disease in Human African trypanosomiasis: the host and parasite genetics of virulence. Parasitology. 2010; 137: 2007–2015. 10.1017/S0031182010000946 - DOI - PubMed

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