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Case Reports
. 2017 May 16;9(5):238-242.
doi: 10.4253/wjge.v9.i5.238.

Successful endoscopic treatment of an intraductal papillary neoplasm of the bile duct

Nikola S Natov  1 , Laura C Horton  1 , Sanjay R Hegde  1
Affiliations
Case Reports

Successful endoscopic treatment of an intraductal papillary neoplasm of the bile duct

Nikola S Natov et al. World J Gastrointest Endosc. .

Abstract

We present a case of a 76-year-old man with right upper quadrant abdominal pain and weight loss, who was found to have an intraductal papillary neoplasm of the bile duct (IPNB) of the pancreaticobiliary subtype, deemed curatively resectable. The patient declined surgery and opted for endoscopic therapy. He underwent two sessions of endoscopic retrograde cholangiopancreatography (ERCP)-guided radiofrequency ablation (RFA). Ten months later, no evidence of recurrence was identified on repeat ERCP. To our knowledge, this is the first reported case of successful use of RFA as a primary treatment modality for resectable IPNB.

Keywords: Ablation technique; Advanced endoscopy; Bile duct neoplasms; Common bile duct diseases; Extrahepatic bile duct.

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Conflict of interest statement

Conflict-of-interest statement: The authors report no financial or other conflicts of interest (including but not limited to commercial, personal, political, intellectual, or religious interests).

Figures

Figure 1
Figure 1
Distal common bile duct stricture on initial cholangiogram.
Figure 2
Figure 2
Polypoid lesion seen with SpyGlass™ cholangioscopy.
Figure 3
Figure 3
Biliary epithelium with papillary configuration and atypical cells.
Figure 4
Figure 4
Occlusion cholangiogram performed four months after last radiofrequency ablation treatment, revealing no polypoid lesion or stricture in the distal common bile duct.
Figure 5
Figure 5
Repeat SpyGlass™ cholangioscopy showing no residual polypoid lesion.
Figure 6
Figure 6
Repeat endoscopic retrograde cholangiopancreatography demonstrating a 10 mm distal common bile duct stricture without evidence of a mass lesion.
See this image and copyright information in PMC

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