Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017:2017:9241459.
doi: 10.1155/2017/9241459. Epub 2017 Apr 23.

A Comparative Study: The Use of Collagen Implant versus Mitomycin-C in Combined Trabeculotomy and Trabeculectomy for Treatment of Primary Congenital Glaucoma

Alaa Abdel Sadek Singab  1 , Osama Ali Mohammed  1 , Mohammed Iqbal Hafez Saleem  1 , Mortada Ahmed Abozaid  1
Affiliations

A Comparative Study: The Use of Collagen Implant versus Mitomycin-C in Combined Trabeculotomy and Trabeculectomy for Treatment of Primary Congenital Glaucoma

Alaa Abdel Sadek Singab et al. J Ophthalmol. 2017.

Abstract

Purpose: To compare Ologen implant versus mitomycin-C (MMC) in combined trabeculotomy and trabeculectomy as a treatment of primary congenital glaucoma.

Setting: Sohag University Hospital, Egypt.

Design: A prospective comparative study.

Methods: Thirty-four eyes of twenty-one patients with primary congenital glaucoma were included in this study. All patients were subjected to preoperative evaluation including complete anterior segment examination under general anesthesia. The patients were divided into two groups: patients of the first group (group A) underwent combined trabeculotomy and trabeculectomy with Ologen implantation while those of the second group (group B) underwent combined trabeculotomy and trabeculectomy with MMC application.

Results: Postoperatively, the IOP in group A was as follows: 8 eyes developed IOP levels less than 14 mmHg (complete success), 3 eyes had levels between 14 and 16 mmHg (accepted result), 2 eyes had levels between 16 and 20 mmHg (guarded result), and only 2 eyes showed levels exceeding 20 mmHg (failed procedure), while in group B, 7 eyes showed complete success, 3 eyes had accepted result, 3 eyes had guarded result, and 2 eyes had failed procedure.

Conclusion: Ologen is a safe and effective adjuvant in combined trabeculotomy and trabeculectomy for treatment of primary congenital glaucoma.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Dickens C. J., Hoskins J. R. H. D. Epidemiology and pathophysiology of congenital glaucoma. In: Ritch R., Shields M. B., Krupin T., editors. The Glaucomas. second. St. Louis: Mosby; 1996. pp. 729–738. - DOI
    1. Mandal A. K., Netland P. A. The Pediatric Glaucomas. 1st. Amsterdam, Netherlands: Elsevier; 2006. Primary congenital glaucoma. - DOI
    1. Dickens C. J., Hoskins J. R. H. D. Diagnosis and treatment of congenital glaucoma. In: Ritch R., Shields M. B., Krupin T., editors. The Glaucomas. second. St. Louis: Mosby; 1996. pp. 739–749. - DOI
    1. Essuman V. A., Braimah I. Z., Ndanu T. A., Ntim-Amponsah C. T. Combined trabeculotomy and trabeculectomy: outcome for primary congenital glaucoma in a West African population. Eye (London, England) 2011;25(1):77–83. doi: 10.1038/eye.2010.156. - DOI - PMC - PubMed
    1. Waheed S., Ritterband D. C., Greenfield D. S., Liebmann J. M., Sidoti P. A., Ritch R. Bleb-related ocular infection in children after trabeculectomy with mitomycin C. Ophthalmology. 1997;104(12):2117–2120. doi: 10.1016/S0161-6420(97)30051-7. - DOI - PubMed

LinkOut - more resources