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Case Reports
. 2017:2017:1256142.
doi: 10.1155/2017/1256142. Epub 2017 May 9.

Antiglomerular Basement Membrane Disease in a Pediatric Patient: A Case Report and Review of the Literature

Vimal Master Sankar Raj  1 , Diana Warnecke  1 , Julia Roberts  2 , Sarah Elhadi  1
Affiliations
Case Reports

Antiglomerular Basement Membrane Disease in a Pediatric Patient: A Case Report and Review of the Literature

Vimal Master Sankar Raj et al. Case Rep Nephrol. 2017.

Abstract

Goodpasture's syndrome (GPS) remains a very rare disease entity in the pediatric population characterized by the presence of pulmonary hemorrhage and rapidly evolving glomerulonephritis. We hereby describe the case of a 2-year-old girl who presented with renal failure and was diagnosed with GPS. A brief review of the literature in regard to data on demographics, pathogenesis, clinical features, diagnosis, treatment, and prognosis for renal recovery is also provided.

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Figures

Figure 1
Figure 1
Chest X-ray on initial presentation.
Figure 2
Figure 2
Trichrome stain showing global glomerulosclerosis.
Figure 3
Figure 3
Glomerulus showing intraglomerular sclerosis.
Figure 4
Figure 4
Immunofluorescence showing linear IgG deposits.
See this image and copyright information in PMC

References

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    1. USRDS U.S. Renal Data System 2015 Annual Data Report: pediatric ESRD. National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Disease, Bethesda. 2015.
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