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. 2017 Oct 1;65(7):1226-1228.
doi: 10.1093/cid/cix513.

Does Disseminated Nontuberculous Mycobacterial Disease Cause False-Positive Determine TB-LAM Lateral Flow Assay Results? A Retrospective Review

Jeremy S Nel  1 , Christopher K Lippincott  2 , Rebecca Berhanu  3 , David C Spencer  4 , Ian M Sanne  5 , Prudence Ive  1
Affiliations

Does Disseminated Nontuberculous Mycobacterial Disease Cause False-Positive Determine TB-LAM Lateral Flow Assay Results? A Retrospective Review

Jeremy S Nel et al. Clin Infect Dis. .

Abstract

We retrospectively reviewed the Determine TB-LAM lateral flow assay (LF-LAM) results among human immunodeficiency virus-infected patients with disseminated nontuberculous mycobacterial (NTM) disease. LF-LAM was positive in 19 of 21 patients without evidence of tuberculosis (TB) coinfection. Although TB-NTM coinfection may have been underdiagnosed, our results suggest that disseminated NTM disease may cause false-positive LF-LAM results.

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