Adipocytes at the Core of Bone Function
- PMID: 28575686
- DOI: 10.1016/j.stem.2017.05.008
Adipocytes at the Core of Bone Function
Abstract
Marrow adipose tissue (MAT) is a specialized adipose tissue with endocrine function found in bone marrow. In this issue of Cell Stem Cell, Ambrosi et al. (2017) identify a stem cell population in the bone marrow that can give rise to both osteogenic and adipogenic MAT precursors and is regulated by diet and aging and affects bone functionality.
Copyright © 2017 Elsevier Inc. All rights reserved.
Comment on
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Adipocyte Accumulation in the Bone Marrow during Obesity and Aging Impairs Stem Cell-Based Hematopoietic and Bone Regeneration.Cell Stem Cell. 2017 Jun 1;20(6):771-784.e6. doi: 10.1016/j.stem.2017.02.009. Epub 2017 Mar 16. Cell Stem Cell. 2017. PMID: 28330582 Free PMC article.
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