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Comment
. 2017 Jun;7(6):555-557.
doi: 10.1158/2159-8290.CD-17-0355.

Toward Molecularly Driven Precision Medicine in Lung Adenocarcinoma

David Liu  1 , Natalie I Vokes  1 , Eliezer M Van Allen  2
Affiliations
Comment

Toward Molecularly Driven Precision Medicine in Lung Adenocarcinoma

David Liu et al. Cancer Discov. 2017 Jun.

Abstract

<b/> Assessing the benefit of routine panel-based genomic sequencing of tumor tissue remains a critical need in clinical oncology. Jordan and coauthors report on 860 patients with metastatic or recurrent lung adenocarcinoma from a single institution with prospectively sequenced tumors using a targeted gene panel of >300 genes to guide therapy. Their results suggest that early prospective tumor sequencing, including non-standard-of-care predictive biomarkers combined with careful clinical annotation, can guide therapy, improve clinical outcomes, and accelerate the development of biomarkers and drugs. Cancer Discov; 7(6); 555-7. ©2017 AACRSee related article by Jordan et al., p. 596.

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Conflict of interest statement

Disclosure of Potential Conflicts of Interest

E.M. Van Allen reports receiving commercial research grants from Novartis and BMS and speakers bureau honoraria from Illumina, has ownership interest in Syapse, and is a consultant/advisory board member for Genome Medical. No potential conflicts of interest were disclosed by the other authors.

Comment on

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