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Review
. 2016 Apr;5(2):211-220.
doi: 10.1016/j.iccl.2015.12.006. Epub 2016 Feb 13.

In-stent Restenosis

Michael S Lee  1 , Gaurav Banka  2
Affiliations
Review

In-stent Restenosis

Michael S Lee et al. Interv Cardiol Clin. 2016 Apr.

Abstract

In-stent restenosis (ISR) is the narrowing of a stented coronary artery lesion. The mean time from percutaneous coronary intervention (PCI) to ISR was 12 months with drug-eluting stents (DES) and 6 months with bare metal stents (BMS). ISR typically presents as recurrent angina. The use of DES has significantly reduced the rate of ISR compared with BMS. Predictors of ISR include patient, lesion, and procedural characteristics. Intravascular ultrasound, optical coherence tomography, and fractional flow reserve are important tools for the anatomic and hemodynamic assessment of ISR. Treatment options for ISR include percutaneous coronary intervention with DES.

Keywords: In-stent restenosis; Neointimal hyperplasia; Percutaneous coronary intervention; Target lesion revascularization; Target vessel revascularization.

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