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Review
. 2017 Jun 6:18:626-630.
doi: 10.12659/ajcr.903580.

Synchronous Gastrointestinal Carcinoid Tumor and Colon Adenocarcinoma: Case Reports and Literature Review

Jessica N Winn  1 , Anjana Sathyamurthy  1 , Jessica L Kneib  2 , Jamal A Ibdah  1 , Veysel Tahan  1
Affiliations
Review

Synchronous Gastrointestinal Carcinoid Tumor and Colon Adenocarcinoma: Case Reports and Literature Review

Jessica N Winn et al. Am J Case Rep. .

Abstract

BACKGROUND Coexistence of carcinoid tumor and colorectal adenocarcinoma is rare. In this report, we present two cases and review the current literature for synchronous carcinoid tumor and colorectal carcinoma occurrence. CASE REPORT In both cases, the rectal carcinoid tumors and sigmoid colon adenocarcinomas were detected by colonoscopy. The colon adenocarcinomas were effectively treated with a laparoscopic sigmoidectomy and the carcinoids were successfully removed endoscopically. Our 40-year-old patient was the youngest among 17 reported patient cases. CONCLUSIONS These two cases demonstrate that the diagnosis of gastrointestinal carcinoid requires a complete assessment of the remainder of the colon for another primary cancer to achieve a timely treatment management strategy.

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Conflict of interest statement

Conflict of interest: None declared

Conflict of interest

All the authors have no conflicts of interests to declare.

Figures

Figure 1.
Figure 1.
(A) Well differentiated neuroendocrine tumor, grade 1 (carcinoid tumor), synaptophysin immunostain at 400× magnification. (B) Moderately differentiated invasive adenocarcinoma, H&E stain at 200× magnification.
Figure 2.
Figure 2.
(A) Well differentiated neuroendocrine tumor (carcinoid tumor), H&E stain at 200× magnification. (B) Moderately differentiated invasive adenocarcinoma, H&E stain at 100× magnification.
See this image and copyright information in PMC

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Supplementary concepts