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Case Reports
. 2017 May-Jun;8(3):208-210.
doi: 10.4103/idoj.IDOJ_118_16.

A Case of Peeling Skin Syndrome

Anil K Singhal  1 , Devendra K Yadav  1 , Bajrang Soni  1 , Savita Arya  1
Affiliations
Case Reports

A Case of Peeling Skin Syndrome

Anil K Singhal et al. Indian Dermatol Online J. 2017 May-Jun.

Abstract

Peeling skin syndrome is a very rare autosomal recessive disease characterized by widespread painless peeling of the skin in superficial sheets. Etiology is still unknown with an autosomal recessive inheritance. Less than 100 cases have been reported in the medical literature. We present a 32-year-old man having asymptomatic peeling of skin since birth. Sheets of skin were peeling from his neck, trunk, and extremities, following friction or rubbing especially if pre-soaked in water but sparing palm and soles. Histologically, there was epidermal separation at the level of stratum corneum, just above the stratum granulosum. This case is being presented due to its rarity.

Keywords: Generalised non inflammatory; keratolytic; peeling skin syndrome.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Trunk showing superficial peeling
Figure 2
Figure 2
Back showing superficial peeling
Figure 3
Figure 3
Sparing of palms (no peeling)
Figure 4
Figure 4
Histopathological figure (H and E stain) ×100 revealed epidermal separation in stratum corneum, thinning of epidermis, and loss of rete ridges. Mild lymphocytic infiltrate was present in epidermis
See this image and copyright information in PMC

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