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. 2017 Jun 6;12(6):e0178462.
doi: 10.1371/journal.pone.0178462. eCollection 2017.

Performance analysis of a new hypersonic vitrector system

Paulo Eduardo Stanga  1   2   3 , Salvador Pastor-Idoate  1   2 , Isaac Zambrano  1   4 , Paul Carlin  1   5 , David McLeod  1   3
Affiliations

Performance analysis of a new hypersonic vitrector system

Paulo Eduardo Stanga et al. PLoS One. .

Abstract

Purpose: To evaluate porcine vitreous flow and water flow rates in a new prototype hypersonic vitrectomy system compared to currently available pneumatic guillotine vitrectors (GVs) systems.

Methods: Two vitrectors were tested, a prototype, ultrasound-powered, hypersonic vitrector (HV) and a GV. Porcine vitreous was obtained within 12 to 24 h of sacrifice and kept at 4°C. A vial of vitreous or water was placed on a precision balance and its weight measured before and after the use of each vitrector. Test parameters included changes in aspiration levels, vitrector gauge, cut rates for GVs, % ultrasound (US) power for HVs, and port size for HVs. Data was analysed using linear regression and t-tests.

Results: There was no difference in the total average mean water flow between the 25-gauge GV and the 25-gauge HV (t-test: P = 0.363); however, 25-gauge GV was superior (t-test: P < 0.001) in vitreous flow. The 23-gauge GV was only more efficient in water and vitreous removal than 23-gauge HV needle-1 (Port 0.0055) (t-test: P < 0.001). For HV, wall thickness and gauge had no effect on flow rates. Water and vitreous flows showed a direct correlation with increasing aspiration levels and % US power (p<0.05).

Conclusions: The HV produced consistent water and vitreous flow rates across the range of US power and aspiration levels tested. Hypersonic vitrectomy may be a promising new alternative to the currently available guillotine-based technologies.

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Conflict of interest statement

Competing Interests: Paulo Stanga: Bausch & Lomb: Consultancy, Equipment, Research Funding, Lecture Fees, Travel expenses, Patent; Salvador Pastor-Idoate: Bausch & Lomb: Research Funding. The sponsor or funding organization had no role in the design or conduct of this research. None of the authors has proprietary interest in this manuscript or patent, and the funding received does not alter our adherence to PLOS ONE policies on sharing data and materials. PATENT No: US 9,498,377 B2. DATE OF PATENT: NOV 22, 2016.

Figures

Fig 1
Fig 1
(A) 23-gauge HV needle (center) compared with 25-gauge (right) and 23-gauge (left) of guillotine needle. (B) High-magnification image of the tip and port of the HV.
Fig 2
Fig 2
(A) Predicted and actual water flow through HV cutter for Vacuum * port area cross term. (B) Predicted and actual water flow through HV device for √Vacuum * port area cross term.
Fig 3
Fig 3. Predicted and actual vitreous flow through HV cutter for vacuum* port area cross term.
Fig 4
Fig 4. Average vitreous flow rate by cutting power for 23-gauge GV and 23-gauge HV cutters.
See this image and copyright information in PMC

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