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Comment
. 2017 Jun 5;41(5):455-456.
doi: 10.1016/j.devcel.2017.05.020.

Tregs Expand the Skin Stem Cell Niche

Valerie Horsley  1 , Shruti Naik  2
Affiliations
Free article
Comment

Tregs Expand the Skin Stem Cell Niche

Valerie Horsley et al. Dev Cell. .
Free article

Abstract

Regulatory T cells (Tregs) are emerging as an essential stem cell niche component that promotes wound repair in adipose, muscle, and lung tissues. Recently in Cell, Ali et al. (2017) report that skin resident Tregs facilitate the proliferation and differentiation of hair follicle stem cells through Notch signaling.

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  • Regulatory T Cells in Skin Facilitate Epithelial Stem Cell Differentiation.
    Ali N, Zirak B, Rodriguez RS, Pauli ML, Truong HA, Lai K, Ahn R, Corbin K, Lowe MM, Scharschmidt TC, Taravati K, Tan MR, Ricardo-Gonzalez RR, Nosbaum A, Bertolini M, Liao W, Nestle FO, Paus R, Cotsarelis G, Abbas AK, Rosenblum MD. Ali N, et al. Cell. 2017 Jun 1;169(6):1119-1129.e11. doi: 10.1016/j.cell.2017.05.002. Epub 2017 May 25. Cell. 2017. PMID: 28552347 Free PMC article.

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