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Comparative Study
. 1985;28(2):229-30.
doi: 10.1007/BF00609698.

Intramuscular bioavailability of chlorazepate as compared to diazepam

A Bertler, S Lindgren, J O Magnusson, H Malmgren
Comparative Study

Intramuscular bioavailability of chlorazepate as compared to diazepam

A Bertler et al. Eur J Clin Pharmacol. 1985.

Abstract

Dipotassium chlorazepate (DPC) and diazepam (DZM) were given i.m. and i.v. to 6 healthy volunteers in doses of 20 mg (48.9 mumol) DPC and 15 mg (52.0 mumol) DZM. The interval between the injections was at least 1 week. Plasma samples were analyzed for DPC and DZM by HPLC. The bioavailability of DPC and DZM after i.m. administration, determined from computer calculated AUCs, was 1.04 and 0.85, respectively.

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