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Comment
. 2017 Jun 7;9(393):eaan8194.
doi: 10.1126/scitranslmed.aan8194.

Driver mutations take the wheel in invasive yet nonmalignant disease

Miles A Miller  1
Affiliations
Comment

Driver mutations take the wheel in invasive yet nonmalignant disease

Miles A Miller. Sci Transl Med. .

Abstract

Despite their low risk for malignant transformation, infiltrating endometriotic lesions harbor cancer-associated mutations.

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  • Cancer-Associated Mutations in Endometriosis without Cancer.
    Anglesio MS, Papadopoulos N, Ayhan A, Nazeran TM, Noë M, Horlings HM, Lum A, Jones S, Senz J, Seckin T, Ho J, Wu RC, Lac V, Ogawa H, Tessier-Cloutier B, Alhassan R, Wang A, Wang Y, Cohen JD, Wong F, Hasanovic A, Orr N, Zhang M, Popoli M, McMahon W, Wood LD, Mattox A, Allaire C, Segars J, Williams C, Tomasetti C, Boyd N, Kinzler KW, Gilks CB, Diaz L, Wang TL, Vogelstein B, Yong PJ, Huntsman DG, Shih IM. Anglesio MS, et al. N Engl J Med. 2017 May 11;376(19):1835-1848. doi: 10.1056/NEJMoa1614814. N Engl J Med. 2017. PMID: 28489996 Free PMC article.

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