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. 1985 Jun;5(2):201-6.
doi: 10.1038/jcbfm.1985.26.

Positron emission tomography in schizophrenic patients with and without neuroleptic medication

L E DeLisi, H H Holcomb, R M Cohen, D Pickar, W Carpenter, J M Morihisa, A C King, R Kessler, M S Buchsbaum

Positron emission tomography in schizophrenic patients with and without neuroleptic medication

L E DeLisi et al. J Cereb Blood Flow Metab. 1985 Jun.

Abstract

Positron emission tomography using [18F]2-fluoro-2-deoxy-D-glucose was performed in nine chronic schizophrenic patients both when medication-free and when medicated with neuroleptics. Total brain cortex, temporal cortex, and basal ganglia glucose use was significantly increased with medication; however, there was no change in anterior/posterior metabolic gradients.

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