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Clinical Trial
. 1985 Apr 27;1(8435):941-3.
doi: 10.1016/s0140-6736(85)91723-4.

Controlled trial of treatment of recurrent spontaneous abortion by immunisation with paternal cells

J F Mowbray, C Gibbings, H Liddell, P W Reginald, J L Underwood, R W Beard
Clinical Trial

Controlled trial of treatment of recurrent spontaneous abortion by immunisation with paternal cells

J F Mowbray et al. Lancet. .

Abstract

In a paired sequential double-blind trial of immunological treatment of recurrent spontaneous abortion successful outcome of the next pregnancy was significantly more common in women injected with purified lymphocytes prepared from their husbands' blood than in those injected with their own lymphocytes. 17 of 22 women given paternal cells had successful pregnancies, compared with 10 of 27 given their own cells.

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