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Comment
. 2018 Mar;20(2):256-259.
doi: 10.1017/cem.2017.35. Epub 2017 Jun 9.

Intensive blood-pressure lowering in patients with acute cerebral hemorrhage

Sufyan Alrahbi  1 , Rashid Alaraimi  1 , Abdalla Alzaabi  1 , Sophie Gosselin  2
Affiliations
Comment

Intensive blood-pressure lowering in patients with acute cerebral hemorrhage

Sufyan Alrahbi et al. CJEM. 2018 Mar.

Abstract

Clinical question Is intensive blood pressure (BP) treatment (systolic BP target 110-139 mm Hg) better than standard antihypertensive treatment (systolic BP target 140-179 mm Hg) in reducing mortality and disability in patients with acute intracerebral hemorrhage (ICH)? Article chosen Qureshi AI, Palesch YY, Barsan WG, et al. Intensive blood-pressure lowering in patients with acute cerebral hemorrhage. N Engl J Med 2016;375(11):1033-43.

Objective: To determine the therapeutic benefit of intensive BP treatment compared to standard BP treatment in reducing death and disability after 3 months of follow-up among patients with ICH treated within 4.5 hours from onset of symptoms.

Keywords: ICH; blood pressure; intensive; intracerebral hemorrhage; labetalol; nicardipine.

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  • Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage.
    Qureshi AI, Palesch YY, Barsan WG, Hanley DF, Hsu CY, Martin RL, Moy CS, Silbergleit R, Steiner T, Suarez JI, Toyoda K, Wang Y, Yamamoto H, Yoon BW; ATACH-2 Trial Investigators and the Neurological Emergency Treatment Trials Network. Qureshi AI, et al. N Engl J Med. 2016 Sep 15;375(11):1033-43. doi: 10.1056/NEJMoa1603460. Epub 2016 Jun 8. N Engl J Med. 2016. PMID: 27276234 Free PMC article. Clinical Trial.

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