Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1985;48(3):229-36.
doi: 10.1007/BF02890131.

Biosynthesis of various types of collagen by human hepatoma cells in vitro

R Uchino, T Nohara, E Okamoto, M Fukumoto, O Midorikawa

Biosynthesis of various types of collagen by human hepatoma cells in vitro

R Uchino et al. Virchows Arch B Cell Pathol Incl Mol Pathol. 1985.

Abstract

A cloned human hepatoma cell line (HH2-1) produced and formed collagen fibers in vitro. The relative rate of collagen synthesis by the cells was increased with an enhancement of the cell density. An analysis of the components of the collagen using sodium dodecyl sulfate-polyacrylamide gel electrophoresis revealed that the cells synthesized interstitial collagen, types I and III, and other collagenous proteins. Thus, human hepatoma cells may play an important role in the formation of stromal collagen in the tumor.

PubMed Disclaimer

LinkOut - more resources