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Clinical Trial
. 1985;19 Suppl 1(Suppl 1):37S-43S.
doi: 10.1111/j.1365-2125.1985.tb02741.x.

A double-blind comparison of alprazolam, diazepam and placebo in the treatment of anxious out-patients

K Davison, R G Farquharson, M C Khan, A Majid
Clinical Trial

A double-blind comparison of alprazolam, diazepam and placebo in the treatment of anxious out-patients

K Davison et al. Br J Clin Pharmacol. 1985.

Abstract

In a double-blind 28-day comparison of alprazolam, diazepam and placebo, alprazolam 1.5-3 mg/day was of equivalent anxiolytic effect to 15-30 mg diazepam/day and there was some evidence of antidepressant activity by alprazolam, but not diazepam, in neurotic depression. No serious side-effects or laboratory abnormalities were encountered.

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