Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2017 Aug;29(4):399-406.
doi: 10.1097/MOP.0000000000000512.

HIV preexposure prophylaxis for adolescents and young adults

Emily Allen  1 , Allegra Gordon, Douglas Krakower, Katherine Hsu
Affiliations
Review

HIV preexposure prophylaxis for adolescents and young adults

Emily Allen et al. Curr Opin Pediatr. 2017 Aug.

Abstract

Purpose of review: The review describes the evidence for HIV preexposure prophylaxis (PrEP) with daily combined tenofovir disoproxil fumarate and emtricitabine for adolescents and young adults. Current recommendations are described, as are the unique medical, socioeconomic, and legal considerations regarding the use of PrEP for youth.

Recent findings: PrEP with daily oral tenofovir disoproxil fumarate-emtricitabine has been shown to help prevent new HIV infection among adults at substantial risk. Evidence suggests a protective benefit of PrEP for youth at risk for HIV, although low adherence is emerging as a barrier to effective use.

Summary: Effective use of antiretrovirals for PrEP represents a seminal development in HIV prevention efforts. Improving access and adherence to PrEP for youth has the potential to substantially reduce the incidence of HIV in this population.

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest

None.

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. UNICEF. For every child, end AIDS – Seventh stocktaking report. 2016.
    1. Rotheram-Borus MJ, Swendeman D, Chovnick G. The Past, Present, and Future of HIV Prevention: Integrating Behavioral, Biomedical, and Structural Intervention Strategies for the Next Generation of HIV Prevention. Annu Rev Clin Psychol. 2009;5:143–67. - PMC - PubMed
    1. US Public Health Service. Preexposure Prophylaxis for the Prevention of HIV Infection in the United States: A Clinical Practice Guideline. 2014.
    1. World Health Organization. Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection: recommendations for a public health approach. World Health Organization; 2016. These guidelines provide evidence-based guidelines regarding HIV testing, prevention, treatment, and care in a global context. - PubMed
    1. Thigpen MC, Kebaabetswe PM, Paxton La, Smith DK, Rose CE, Segolodi TM, et al. Antiretroviral Preexposure Prophylaxis for Heterosexual HIV Transmission in Botswana. N Engl J Med. 2012;367(5):423–34. - PubMed

MeSH terms

Substances