Heavy Metal to Rock the Immune Infiltrate
- PMID: 28602618
- DOI: 10.1016/j.it.2017.05.007
Heavy Metal to Rock the Immune Infiltrate
Abstract
Two resource articles recently published in Cell demonstrate that the elevated phenotypic complexity of the immune infiltrate in human lung adenocarcinomas and renal cell carcinomas can be reliably dissected with mass cytometry. These findings may pave the way to a new era of precision cancer immunotherapy.
Keywords: CD4(+)CD25(+)FOXP3(+) regulatory T cells; CD8(+) cytotoxic T lymphocytes; dendritic cells; immune checkpoint blockers; natural killer cells; tumor-associated macrophages.
Copyright © 2017 Elsevier Ltd. All rights reserved.
Comment on
-
An Immune Atlas of Clear Cell Renal Cell Carcinoma.Cell. 2017 May 4;169(4):736-749.e18. doi: 10.1016/j.cell.2017.04.016. Cell. 2017. PMID: 28475899 Free PMC article.
-
Innate Immune Landscape in Early Lung Adenocarcinoma by Paired Single-Cell Analyses.Cell. 2017 May 4;169(4):750-765.e17. doi: 10.1016/j.cell.2017.04.014. Cell. 2017. PMID: 28475900 Free PMC article.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Research Materials
