Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2017 Aug;32(8):1147-1154.
doi: 10.1002/mds.27027. Epub 2017 Jun 12.

Personalized medicine in Parkinson's disease: Time to be precise

Nataliya Titova  1 , K Ray Chaudhuri  2   3   4
Affiliations

Personalized medicine in Parkinson's disease: Time to be precise

Nataliya Titova et al. Mov Disord. 2017 Aug.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
A diagram of potential factors to consider which may drive or enable pathways for personalized and precision medicine in PD.
Figure 2
Figure 2
Proposed types of personalized medicine applicable to PD. [Color figure can be viewed at wileyonlinelibrary.com]
Figure 3
Figure 3
An example of how precision medicine based “cocktail” therapy could be applied in the context of genomic personalized medicine in patients carrying the glucocerebrocidase mutation in PD. GBA, glucocerebrocidase gene; GCase, glucocerebrocidase; AAV, adeno‐associated virus. [Color figure can be viewed at wileyonlinelibrary.com]
Figure 4
Figure 4
A circle of components of lifestyle that will help complete delivery of personalized medicine. [Color figure can be viewed at wileyonlinelibrary.com]
Figure 5
Figure 5
A summary of the various components of and strategies proposed to establish a comprehensive and holistic personalized medicine strategy.
See this image and copyright information in PMC

References

    1. Titova N, Padmakumar C, Lewis SJ, Chaudhuri KR. Parkinson's: a syndrome rather than a disease? [published online ahead of print December 27, 2016]. J Neural Transm (Vienna). doi: - DOI - PMC - PubMed
    1. Jellinger KA. Neuropathobiology of non‐motor symptoms in Parkinson disease. J Neural Transm (Vienna) 2015;122(10):1429‐1440. - PubMed
    1. Sauerbier A, Jenner P, Todorova A, Chaudhuri KR. Non motor subtypes and Parkinson's disease. Parkinsonism Relat Disord 2016;22(suppl 1):S41‐S46. - PubMed
    1. Marras C, Chaudhuri KR. Nonmotor features of Parkinson's disease subtypes. Mov Disord 2016;31(8):1095‐1102. - PubMed
    1. Miller DB, O'Callaghan JP. Biomarkers of Parkinson's disease: present and future. Metabolism 2015;64(3 suppl 1):S40‐S46. - PMC - PubMed