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Review
. 2017 Dec;17(12):1203-1212.
doi: 10.1002/tcr.201700021. Epub 2017 Jun 12.

Manganese-Mediated Homolytic Aromatic Substitution with Phosphinylidenes

Olivier Berger  1 , Jean-Luc Montchamp  1
Affiliations
Review

Manganese-Mediated Homolytic Aromatic Substitution with Phosphinylidenes

Olivier Berger et al. Chem Rec. 2017 Dec.

Abstract

Carbon-phosphorus (C-P) bond-forming reactions via homolytic aromatic substitution (HAS) of non-functionalized substrates with phosphinylidene P(O)H compounds is becoming a useful synthetic tool for the preparation of aryl and heteroaryl phosphonates, phosphinates, and phosphine oxides. This review specifically covers recent work using manganese-mediated free radical processes. Several research groups employ expensive Mn(OAc)3 , whereas our own contributions focus on the novel and inexpensive Mn(OAc)2 /MnO2 system.

Keywords: arylation; homolytic aromatic substitution; manganese; phosphinate; phosphonate.

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